New ERGO Feature: MetaCyc/EcoCyc/BioCyc Pathway Database Integration

We’re always aiming to improve the breadth and depth of data we provide to our clients. This is why we’ve integrated SRI’s MetaCyc* and EcoCyc* databases into ERGO. This adds over 3000 new pathways to ERGO. BioCyc functional assignments are computed for every genome in the ERGO database.

The pathway diagrams are drawn using a subset of the System Biology Graphical Notation. The pathway diagrams are completely interactive and can be customized and rearranged to your preference. Each pathway has a summary description and background so that the researcher can completely understand its context.

RNA-Seq and other expression data can be interactively projected onto the BioCyc pathways. BioCyc is also one of the ontologies available for Gene Set Enrichment Analysis (GSEA) and on differential gene expression plots.

ERGO’s differential analysis and GSEA plots can help you quickly identify which pathways are changing under your experimental conditions.

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*BioCyc TM pathway/genome databases under license from SRI International. (https://www.biocyc.org).